Sneezing, sniffles, hives, headaches and dizziness— what do allergy symptoms have in common with PMS?

Many women don’t realize that a histamine intolerance may be the cause of their period pain.

Histamines are chemicals that are stored in mast cells which are a type of immune cell. Estrogen causes the release of histamine from mast cells in the uterus and ovaries. If you have higher estrogen levels, it can cause an increase in histamine levels and vice versa.